Overview
Epitalon is classified as a telomerase activator peptide. Anti-aging, longevity, sleep.
Lengthens telomeres via telomerase activation. May also regulate melatonin production and circadian rhythm, and modulate antioxidant enzyme activity.
Also known as: Epithalon, AEDG peptide
Category
Telomerase Activator
Half-Life
2h
Route
SubQ
FDA Status
Not Approved
How Does Epitalon Work?
Lengthens telomeres via telomerase activation. May also regulate melatonin production and circadian rhythm, and modulate antioxidant enzyme activity.
At the molecular level, Epitalon operates through pathways characteristic of the Telomerase Activator class, interacting with target receptors and downstream signaling cascades to produce its observed effects.
Published Research
The following studies are indexed from PubMed and peer-reviewed journals:
[1]Epitalon lifespan extension in animals
Anisimov et al. (Biogerontology): Extends lifespan in multiple animal models by 10-15% via telomerase activation and melatonin regulation.
Evidence: preclinical[2]Epitalon activates telomerase and lengthens telomeres in human cells
Khavinson et al. demonstrate Epitalon activates telomerase catalytic subunit (hTERT) expression in human fetal fibroblasts, extending replicative lifespan by 10 population doublings.
Evidence: preclinical[3]Epitalon geroprotective effects: 25-year comprehensive review
Comprehensive 25-year review of Epitalon's antioxidant, neuroprotective, antimutagenic, and anti-cancer properties across in vitro, in vivo, and in silico models.
Evidence: preclinical[4]Epithalamin (parent compound) regulates melatonin in elderly
Korkushko et al.: Epithalamin administration normalizes melatonin production and circadian rhythm in elderly patients, improving sleep and immune function.
Evidence: moderateSafety Profile
Research-only. Telomerase activation carries theoretical cancer risk. Long-term safety unknown.
| Side Effect | Incidence | Severity |
|---|---|---|
| Generally very well-tolerated | Based on Russian clinical research | mild |
| Mild fatigue | ~3% of users | mild |
Sourcing Epitalon for Research
If you're looking to source Epitalon for laboratory research, our vendor directory compares pricing, purity testing, and COA verification from independently vetted suppliers.
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Full Research Profile
Epitalon — dosing, interactions, timelines & more
Comprehensive compound profile with sourcing information, stacking synergies, and outcome timelines.