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⚠️ Educational only · Not medical advice · Consult a doctor · Most peptides are research-only / not FDA-approved for human use

Follistatin-344

Also: FS-344

💪Myostatin Inhibitor

How It Works

Blocks myostatin (the body's muscle growth limiter) and activin, allowing enhanced muscle development and regeneration beyond normal physiological limits.

Primary Benefits

1Muscle hypertrophy
2strength

Key Studies

Follistatin gene therapy increases muscle mass and strength

Rodino-Klapac et al. (Mol. Ther.): AAV-delivered follistatin 344 increases muscle mass and fiber diameter across multiple animal species without adverse reproductive or endocrine effects.

preclinical

Follistatin as myostatin antagonist therapeutic potential

Kalista et al.: Review of follistatin's role as primary endogenous myostatin antagonist and its therapeutic potential for muscular dystrophies and sarcopenia.

preclinical

Follistatin gene transfer for Becker muscular dystrophy (Phase I)

Mendell et al. (Mol. Ther.): Phase I clinical trial of AAV1-follistatin gene transfer in Becker muscular dystrophy patients shows improved 6-minute walk test with no adverse effects.

moderate

Follistatin in adipocyte differentiation and energy metabolism

Research demonstrating follistatin's broader metabolic role in adipocyte browning, energy expenditure, and metabolic health beyond muscle hypertrophy.

preclinical

Safety Notes

Research-only. Potent effects potential for unregulated growth. Limited human safety data. Phase I gene therapy trials show safety.

Dosing Protocol

⚠️ For educational purposes only. Not medical advice. Consult a healthcare professional before using any peptide.

RouteSubQ
Dose Range100-200 mcg
FrequencyDaily
TimingPost-workout or morning
Cycle Length2-4 weeks
BAC Water1 ml / 1mg vial

Very short cycles. 100mcg/day common. Acts via myostatin/activin inhibition effects compound over days.

Half-Life Visualization

⏱️ Half-Life: 6h

Plasma concentration over time
100%50%0%0t½ = 6h

Legal Status by Country

🇺🇸USA
Research Only
🇨🇦Canada
Research Only
🇬🇧UK
Unregulated
🇪🇺EU
Unregulated
🇦🇺Australia
Research Only

Last updated: 2026-01 · Laws change frequently. Verify current status in your jurisdiction.

Expected Timeline

Weeks 2-4

Initial myostatin inhibition; muscle fullness and pumps

Month 2-3

Measurable lean mass increase; strength gains

Long-term

Very limited long-term human data; Phase I gene therapy shows safety

Side Effects & Incidence

Side EffectIncidenceSeverity

Limited human safety data

Investigational onlymild

Injection site reaction

~5% of usersmild

Theoretical cancer promotion

Myostatin inhibition could allow unregulated cell growth

Mechanism-based concernrare

Incidence rates sourced from published clinical trial data where available; otherwise based on community research observations.

Found in 1 Stack

Muscle Growth Stack

Maximize lean muscle gain through GH optimization, growth factor signaling, and myostatin inhibition

CJC-1295IpamorelinSermorelinFollistatin-344IGF-1 LR3

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