Peptide Research Index
⚠️ Educational only · Not medical advice · Consult a doctor · Most peptides are research-only / not FDA-approved for human use
⚠️ Educational only · Not medical advice · Consult a doctor · Most peptides are research-only / not FDA-approved for human use
Also: Growth Hormone Releasing Peptide-2, Pralmorelin, KP-102
GHRPLast Updated: April 1, 2026
GHRP-2 (also known as Growth Hormone Releasing Peptide-2, Pralmorelin, KP-102) is a prominently researched experimental compound classified strictly within the GHRP framework. Operating primarily through advanced pharmacological pathways, it functions by synthetic hexapeptide GH secretagogue acting on the GHSR1a receptor. GHRP-2 produces the most potent GH release among standard GHRPs (stronger than GHRP-6 or Ipamorelin) but with moderate increases in cortisol and prolactin. Approved in Japan as a diagnostic tool for GH deficiency (trade name: Pralmorelin/GHRP Kaken). with a documented biological half-life of roughly 1.5 hours, in preclinical investigative trials and independent academic studies, researchers utilizing GHRP-2 have documented significant, quantifiable biological outcomes, primarily focusing on strongest gh release of standard ghrps, muscle growth, anti-aging, recovery. Typical research protocols investigate administering 100 to 300mcg via subq pathways 1-3x daily. However, it is critically important to understand that while GHRP-2 demonstrates profound physiological potential in highly controlled laboratory settings, it remains classified strictly as a research chemical and has not been approved by the United States Food and Drug Administration (FDA) for human therapeutic, diagnostic, or dietary consumption. Independent chemical analysis via rigorous third-party Certificate of Analysis (COA) testing utilizing High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) remains the industry gold standard for verifying its base elemental stability when reconstituted appropriately in sterile bacteriostatic water.
Synthetic hexapeptide GH secretagogue acting on the GHSR1a receptor. GHRP-2 produces the most potent GH release among standard GHRPs (stronger than GHRP-6 or Ipamorelin) but with moderate increases in cortisol and prolactin. Approved in Japan as a diagnostic tool for GH deficiency (trade name: Pralmorelin/GHRP Kaken).
Arvat et al. (J. Clin. Endocrinol. Metab.): GHRP-2 produces the strongest GH response among tested GHRPs in healthy adults, with dose-dependent effects and moderate prolactin/cortisol elevation.
moderateClinical validation of GHRP-2 (Pralmorelin) as a diagnostic GH provocative test in Japan, showing reliable, reproducible GH stimulation for diagnosing adult GH deficiency.
strongFrieboes et al.: GHRP-2 enhances slow-wave sleep and amplifies nocturnal GH pulses in healthy young men, supporting pre-bed dosing protocols.
moderateBowers et al.: Chronic GHRP-2 administration in elderly subjects increases IGF-1, GH, and lean body mass while reducing fat mass.
moderateThe most potent standard GHRP. Approved in Japan as a diagnostic tool (Pralmorelin). Raises cortisol and prolactin more than Ipamorelin but less than Hexarelin. Not FDA-approved for therapeutic use.
⚠️ For educational purposes only. Not medical advice. Consult a healthcare professional before using any peptide.
Most common dose: 150-300mcg per injection. Empty stomach required. Often considered the 'goldilocks' GHRP: stronger than Ipamorelin, fewer sides than GHRP-6.
Week 1
Improved sleep quality; moderate appetite increase; GH flush sensation
Weeks 2-4
Enhanced recovery; early body composition shifts; IGF-1 elevation on bloodwork
Month 2-3
Significant lean mass improvement; fat redistribution; skin quality enhancement
Long-term
Sustained somatotropic axis support; cycling recommended every 12-16 weeks
| Side Effect | Incidence | Severity |
|---|---|---|
Moderate appetite increase Less intense than GHRP-6 but more than Ipamorelin | ~30% of users | mild |
Cortisol elevation (transient) | ~20% of users | mild |
Prolactin elevation (transient) Monitor if stacking with other prolactin-raising compounds | ~15% of users | mild |
Water retention | ~12% of users | mild |
Drowsiness / fatigue | ~8% of users | mild |
Incidence rates sourced from published clinical trial data where available; otherwise based on community research observations.
Finding verified, high-purity GHRP-2 requires rigorous COA verification. We independently evaluate vendors based on third-party HPLC testing, purity thresholds (≥98%), and batch-specific documentation.
View COA-Verified GHRP-2✓ Third-party tested·✓ US shipping·✓ COA on every batch
Disclosure: PeptiDex may earn a commission from purchases made through affiliate links. This does not affect our editorial independence or recommendations. We exclusively feature vendors that pass our strict quality verification protocols.
PeptiDex. (2026). GHRP-2. PeptiDex Research Platform. https://peptidex.app/library/ghrp-2
12 stacks • exact dosages • cycle lengths • printable reference
No spam. Unsubscribe anytime.