PeptiDex
Peptide Research Index
Research-backed
Peptide Research Index
⚠️ Educational only · Not medical advice · Consult a doctor · Most peptides are research-only / not FDA-approved for human use
⚠️ Educational only · Not medical advice · Consult a doctor · Most peptides are research-only / not FDA-approved for human use
Also: GSH, L-Glutathione, Gamma-Glutamylcysteinylglycine, Reduced Glutathione
🛡️AntioxidantGlutathione is the body's master antioxidant — a tripeptide (glutamate-cysteine-glycine) present in every cell. It neutralizes reactive oxygen species, regenerates vitamins C and E, supports Phase II liver detoxification, and modulates immune cell function. Injectable GSH bypasses poor oral bioavailability.
Forman et al. (Mol. Aspects Med.): Comprehensive review of glutathione's role in redox signaling, detoxification, and its depletion in disease states including Parkinson's, liver disease, and cancer.
strongDröge & Breitkreutz (Proc. Nutr. Soc.): Review demonstrating glutathione's critical role in lymphocyte proliferation, NK cell activity, and overall immune defense.
moderateWeschawalit et al. (Clin. Cosmet. Investig. Dermatol.): RCT showing oral glutathione supplementation significantly reduces melanin index and improves skin elasticity and wrinkles.
moderateSian et al.: Early landmark study demonstrating reduced glutathione levels as one of the earliest biochemical changes in Parkinson's disease pathology.
strongExcellent safety profile. Used clinically for decades. IV and SubQ routes well-tolerated. Rare allergic reactions possible. May reduce effectiveness of some chemotherapy drugs — avoid during cancer treatment without oncologist approval.
⚠️ For educational purposes only. Not medical advice. Consult a healthcare professional before using any peptide.
SubQ: 200-600mg. IV push: 600-2000mg. For skin brightening, consistent dosing over 8-12 weeks is needed. Often combined with Vitamin C for synergistic antioxidant effect.
Week 1
Improved energy and reduced oxidative stress markers
Weeks 2-4
Skin brightening begins; improved liver function markers
Month 2-3
Noticeable skin lightening effect; improved immune markers; better hangover recovery
Long-term
Sustained antioxidant protection; potential neuroprotective benefits
| Side Effect | Incidence | Severity |
|---|---|---|
Injection site redness | ~5% of users | mild |
Mild bloating (oral) | ~8% of users | mild |
Rare allergic reaction | <1% of users | rare |
Incidence rates sourced from published clinical trial data where available; otherwise based on community research observations.
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