Thymosin Alpha-1
Last reviewed May 27, 2026
Also known as: Tα1, Zadaxin
Quick Answer
Thymosin Alpha-1 is a immune peptide research compound (not FDA-approved for human use) studied for immune support. Thymosin Alpha-1 is an immune-modulating peptide approved in over 35 countries for treating hepatitis B and C, studied for enhancing T-cell activity and immune resilience against infection. Research dose: 1.50–1.50 mg 2x/wk. Half-life: 2 hours. Available from COA-verified vendors with code PEPTIDEX for up to 20% off.
Where to Source
Ranked by $/mg1Bio Longevity Labs Best $/mg
$110.47
$129.97Save $19.50
10mg vial
$13.00/mg
99%+ purityTested May 2026
Use code for 15% off:
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Rankings independent · Research use only
Enhances T-cell function, boosts dendritic cell activity, and modulates cytokine production. Shifts immune response toward effective pathogen clearance.
Where to Buy Thymosin Alpha-1
COA-verified vendors · Use code PEPTIDEX for up to 20% off
* Prices for research peptide acquisition. Not therapeutic products.
| Vendor | Purity | List Price | With PEPTIDEX | Code | Shop |
|---|---|---|---|---|---|
| 98%+ | $78.0010 mg | $39.00Save 50% | PEPTIDEX | * Research vendor — verify your regional regulations before purchase. Shop | |
| 99%+ | $129.9710 mg | $110.47Save 15% | PEPTIDEX | * Research vendor — verify your regional regulations before purchase. Shop |
$78.00 · 10 mg$39.00−50%
Use code PEPTIDEX for 50% off at Ascension Peptides.
* Research vendor — verify your regional regulations before purchase.
Shop at Ascension Peptides$129.97 · 10 mg$110.47−15%
Use code PEPTIDEX for 15% off at Bio Longevity Labs.
* Research vendor — verify your regional regulations before purchase.
Shop at Bio Longevity Labs§ Mechanism of Action
Enhances T-cell function, boosts dendritic cell activity, and modulates cytokine production. Shifts immune response toward effective pathogen clearance.
§ Primary Benefits
- 1Immune support
- 2antiviral
- 3recovery
§ Clinical Evidence
Thymosin Alpha-1 in immune-compromised patients
Garaci et al.: Review of Tα1 use in immune-compromised patients showing enhanced T-cell function, improved dendritic cell activity, and cytokine modulation.
Moderate-StrongThymosin Alpha-1 safety/efficacy: review of 30+ clinical trials
King & Tuthill: Comprehensive review of 30+ clinical trials involving 11,000+ subjects confirming Tα1's consistent safety and efficacy across hepatitis B/C, cancer, and infections.
StrongThymosin Alpha-1 as adjunct in hepatitis B treatment
Mutchnick et al. (Hepatology): Randomized trial showing Tα1 combined with interferon significantly improves virologic response in chronic hepatitis B vs. interferon alone.
StrongThymosin Alpha-1 in sepsis and critical care
Evidence review of Tα1 in septic shock, ARDS, and peritonitis showing improved survival and immune recovery in critically ill patients.
Moderate-StrongThymosin Alpha-1 as cancer immunotherapy adjuvant
Garaci et al. (Ann. N.Y. Acad. Sci.): Review of Tα1 as cancer immunotherapy adjunct, showing enhanced chemotherapy tolerance and improved immune recovery in multiple tumor types.
ModerateMechanism and clinical application of thymosin in the treatment of lung cancer.
A study published in Frontiers in immunology investigating the effects and mechanisms.
ModerateSerum thymosin alpha 1 levels in normal and pathological conditions.
A study published in Expert opinion on biological therapy investigating the effects and mechanisms.
PreclinicalThymosin α-1 in cancer therapy: Immunoregulation and potential applications.
A study published in International immunopharmacology investigating the effects and mechanisms.
PreclinicalThymosin α1 reverses oncolytic adenovirus-induced M2 polarization of macrophages to improve antitumor immunity and therapeutic efficacy.
A study published in Cell reports. Medicine investigating the effects and mechanisms.
PreclinicalThymosin alpha 1 and HIV-1: recent advances and future perspectives.
A study published in Future microbiology investigating the effects and mechanisms.
Preclinical§ Safety Profile
Approved in 35+ countries for hep B/C. One of the most extensively studied peptides. Not FDA-approved in US.
See our evidence grading methodology for how we evaluate and grade peptide safety data.
§ Dosing Protocol
* Dosing data from published literature — not a human use recommendation.
RouteSubQ
Dose Range1500–1500 mcg
Frequency2x/wk
TimingAny time
Cycle Length12–12 weeks
BAC Water2.5 ml / 5mg vial
Standard dose: 1.6mg 2x/week. Approved in 35+ countries. Higher doses for active infection.
§ Pharmacokinetics
⏱️ Half-Life: 2h
Plasma concentration over time§ Regulatory
🇺🇸USA
Research Only🇨🇦Canada
Research Only🇬🇧UK
Unregulated🇪🇺EU
FDA/TGA Approved🇦🇺Australia
Prescription OnlyLast updated: 2026-01 · Laws change frequently. Verify current status in your jurisdiction.
§ Expected Outcomes
Week 1
NK cell and T-cell activation begins; improved energy if immune-suppressed
Weeks 2–4
Enhanced immune response to pathogens; reduced frequency of illness
Month 2–3
Sustained immune modulation; improved recovery from illness
Long-term
Long-term immune resilience; approved use in 35+ countries for hepatitis therapy
§ Adverse Effects
| Side Effect | Incidence | Severity |
|---|---|---|
Injection site reaction | ~5% of users | mild |
Mild flu-like symptoms (immune activation) Indicates immune activation; usually transient | ~5% of users | mild |
Where to Source Thymosin Alpha-1 for Research
Finding verified, high-purity Thymosin Alpha-1 requires rigorous COA verification. We independently evaluate vendors based on third-party HPLC testing, purity thresholds (≥98%), and batch-specific documentation.
View COA-Verified Thymosin Alpha-1✓ Third-party tested·✓ US shipping·✓ COA on every batch
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§ Comparisons
§ Community Stacks
Immune Support Stack
Strengthen adaptive immune function and provide direct defense against pathogenic threats
Cite This Page
⚠️ Educational only · Not medical advice · For research use only. Information on this page is compiled from peer-reviewed literature and is intended strictly for educational and informational purposes. Peptides discussed may be unapproved research chemicals — consult a licensed healthcare professional before considering any peptide compound. Read our full disclaimer
Affiliate disclosure: PeptiDex may earn commissions from purchases made through vendor links on this page. This does not affect our editorial ranking or vendor recommendations — we exclusively feature vendors that pass independent COA verification. See our methodology · Editorial policy
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Independent researcher, not a medical professional
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