Overview
CJC-1295 is classified as a ghrh analog peptide. Muscle growth, fat loss, recovery.
Stimulates prolonged GH and IGF-1 release by mimicking the body's natural GHRH signal to the pituitary gland. Preserves natural pulsatile GH release pattern.
Also known as: CJC-1295 DAC, Mod GRF 1-29
Category
GHRH Analog
Half-Life
168h
Route
SubQ
FDA Status
Not Approved
How Does CJC-1295 Work?
Stimulates prolonged GH and IGF-1 release by mimicking the body's natural GHRH signal to the pituitary gland. Preserves natural pulsatile GH release pattern.
At the molecular level, CJC-1295 operates through pathways characteristic of the GHRH Analog class, interacting with target receptors and downstream signaling cascades to produce its observed effects.
Published Research
The following studies are indexed from PubMed and peer-reviewed journals:
[1]CJC-1295 GH/IGF-1 elevation in humans
Teichman et al. (J. Clin. Endocrinol. Metab.): Single injection increases GH 2-10x for 6+ days and IGF-1 1.5-3x for 9-11 days in healthy adults. Well-tolerated at 30-60 µg/kg.
Evidence: moderate[2]CJC-1295 preserves pulsatile GH secretion in humans
Ionescu & Bhatt (J. Clin. Endocrinol. Metab.): Demonstrates 7.5-fold increase in basal GH, 46% increase in mean GH, and 45% increase in IGF-1 while preserving natural pulsatile pattern.
Evidence: moderate[3]Long-acting GHRH analogs increase pituitary GH mRNA
Animal study shows CJC-1295 increases total pituitary RNA and GH mRNA, suggesting proliferation of somatotroph cells for sustained GH production.
Evidence: preclinicalSafety Profile
Often stacked with Ipamorelin; injection site reactions possible. Not FDA-approved.
| Side Effect | Incidence | Severity |
|---|---|---|
| Water retention | ~15% of users | mild |
| Headache / GH flush | ~8% of users | mild |
| Injection site reaction | ~5% of users | mild |
| Temporary fatigue | ~5% of users | mild |
Sourcing CJC-1295 for Research
If you're looking to source CJC-1295 for laboratory research, our vendor directory compares pricing, purity testing, and COA verification from independently vetted suppliers.
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Full Research Profile
CJC-1295 — dosing, interactions, timelines & more
Comprehensive compound profile with sourcing information, stacking synergies, and outcome timelines.