PeptiDex
Peptide Research Index
Research-backed
Peptide Research Index
⚠️ Educational only · Not medical advice · Consult a doctor · Most peptides are research-only / not FDA-approved for human use
⚠️ Educational only · Not medical advice · Consult a doctor · Most peptides are research-only / not FDA-approved for human use
Also: CJC-1295 DAC, Mod GRF 1-29
💉GHRH AnalogStimulates prolonged GH and IGF-1 release by mimicking the body's natural GHRH signal to the pituitary gland. Preserves natural pulsatile GH release pattern.
Teichman et al. (J. Clin. Endocrinol. Metab.): Single injection increases GH 2-10x for 6+ days and IGF-1 1.5-3x for 9-11 days in healthy adults. Well-tolerated at 30-60 µg/kg.
moderateIonescu & Bhatt (J. Clin. Endocrinol. Metab.): Demonstrates 7.5-fold increase in basal GH, 46% increase in mean GH, and 45% increase in IGF-1 while preserving natural pulsatile pattern.
moderateAnimal study shows CJC-1295 increases total pituitary RNA and GH mRNA, suggesting proliferation of somatotroph cells for sustained GH production.
preclinicalOften stacked with Ipamorelin; injection site reactions possible. Not FDA-approved.
⚠️ For educational purposes only. Not medical advice. Consult a healthcare professional before using any peptide.
CJC-1295 DAC version has 7-day half-life. Mod GRF 1-29 (no DAC) has ~30min half-life.
Last updated: 2026-01 · Laws change frequently. Verify current status in your jurisdiction.
Week 1
Improved sleep depth; occasional GH flush sensation; increased hunger in morning
Weeks 2-4
Elevated energy and faster post-workout recovery; mild water retention
Month 2-3
Measurable lean mass improvements; visible fat redistribution; IGF-1 elevation confirmed on bloodwork
Long-term
Sustained GH axis support; anti-aging body composition benefits; improved bone density over 6+ months
| Side Effect | Incidence | Severity |
|---|---|---|
Water retention Usually resolves after first 2-4 weeks | ~15% of users | mild |
Headache / GH flush | ~8% of users | mild |
Injection site reaction | ~5% of users | mild |
Temporary fatigue | ~5% of users | mild |
Incidence rates sourced from published clinical trial data where available; otherwise based on community research observations.
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