PeptiDex
Peptide Research Index
Research-backed
Peptide Research Index
⚠️ Educational only · Not medical advice · Consult a doctor · Most peptides are research-only / not FDA-approved for human use
⚠️ Educational only · Not medical advice · Consult a doctor · Most peptides are research-only / not FDA-approved for human use
Selective GH secretagogue that mimics ghrelin at the GHS receptor. Does not significantly raise cortisol or prolactin, making it one of the most selective GH-releasing peptides.
Raun et al. (Eur. J. Endocrinol.): First characterization showing Ipamorelin releases GH potently and selectively without raising ACTH, cortisol, prolactin, FSH, LH, or TSH in swine.
moderateDose-escalation study in healthy humans demonstrates Ipamorelin induces single-episode GH release with peak at ~0.67 hours and terminal half-life of 2 hours.
moderateSvensson et al. show Ipamorelin induces dose-dependent longitudinal bone growth and counters glucocorticoid-induced decreases in bone formation and muscle strength.
preclinicalPreclinical evidence demonstrates Ipamorelin alleviates delayed gastric emptying and post-surgical ileus, suggesting applications beyond hormone optimization.
preclinicalOne of the safest GH peptides. Side effects may include transient headache, flushing. Not FDA-approved.
⚠️ For educational purposes only. Not medical advice. Consult a healthcare professional before using any peptide.
Most commonly dosed at 200-300mcg per injection. Best taken on empty stomach 2+ hrs after eating.
Last updated: 2026-01 · Laws change frequently. Verify current status in your jurisdiction.
Week 1
Improved sleep quality; increased hunger around dosing window
Weeks 2-4
Improved recovery and energy; early body composition shifts
Month 2-3
Visible lean mass gains; fat loss (especially combined with CJC-1295)
Long-term
Sustained IGF-1 support; preserved muscle during caloric deficit
| Side Effect | Incidence | Severity |
|---|---|---|
Temporary hunger | ~12% of users | mild |
Headache | ~5% of users | mild |
Water retention | ~8% of users | mild |
Flushing / warmth | ~4% of users | mild |
Incidence rates sourced from published clinical trial data where available; otherwise based on community research observations.
Maximize fat loss while preserving or building lean muscle the gold standard for total body transformation
Maximize lean muscle gain through GH optimization, growth factor signaling, and myostatin inhibition
Optimize sleep quality, enhance nightly recovery, and improve hormonal output during sleep
Support healthy testosterone levels and hormonal balance while preserving fertility
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