Overview
Selank is classified as a anxiolytic peptide peptide. Anxiety reduction, mental clarity, mood.
Modulates GABA/serotonin neurotransmitter systems. Enhances immune function by influencing IL-6 and T-helper cell balance. Stabilizes enkephalin levels.
Also known as: TP-7
Category
Anxiolytic Peptide
Half-Life
0.5h
Route
Nasal
FDA Status
Not Approved
How Does Selank Work?
Modulates GABA/serotonin neurotransmitter systems. Enhances immune function by influencing IL-6 and T-helper cell balance. Stabilizes enkephalin levels.
At the molecular level, Selank operates through pathways characteristic of the Anxiolytic Peptide class, interacting with target receptors and downstream signaling cascades to produce its observed effects.
Published Research
The following studies are indexed from PubMed and peer-reviewed journals:
[1]Selank anxiolytic effects in humans
Clinical trial demonstrates Selank's anxiolytic efficacy in patients with generalized anxiety disorder, comparable to benzodiazepines but without sedation or dependence.
Evidence: moderate[2]Selank anti-anxiety effects comparable to benzodiazepines
Study confirms Selank provides significant anti-anxiety effects comparable to benzodiazepine treatment, with added cognitive enhancement and no addictive potential.
Evidence: moderate[3]Selank increases BDNF in hippocampus and prefrontal cortex
Selank increases BDNF production in the rat hippocampus and prefrontal cortex, preventing ethanol-induced memory impairment and enhancing synaptic plasticity.
Evidence: preclinical[4]Selank modulates GABA receptor gene expression
Molecular study showing Selank influences GABA-A receptor subunit gene expression, providing mechanism for its anxiolytic effects without sedation.
Evidence: preclinicalSafety Profile
Very safe profile. No reported dependence or withdrawal. Approved as anxiolytic in Russia. Not FDA-approved in US.
| Side Effect | Incidence | Severity |
|---|---|---|
| Mild fatigue | ~5% of users | mild |
| Nasal irritation | ~6% of users | mild |
| Mood fluctuation | ~3% of users | mild |
Sourcing Selank for Research
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Full Research Profile
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Comprehensive compound profile with sourcing information, stacking synergies, and outcome timelines.