Overview
Tesofensine is classified as a small molecule peptide. Extreme fat loss and appetite suppression without GLP-1 side effects.
Triple monoamine reuptake inhibitor (inhibits reuptake of serotonin, noradrenaline, and dopamine). Originates as an Alzheimer's/Parkinson's drug but abandoned due to massive weight loss profiles.
Also known as: NS2330
Category
Small Molecule
Half-Life
216h
Route
Oral
FDA Status
Not Approved
How Does Tesofensine Work?
Triple monoamine reuptake inhibitor (inhibits reuptake of serotonin, noradrenaline, and dopamine). Originates as an Alzheimer's/Parkinson's drug but abandoned due to massive weight loss profiles.
At the molecular level, Tesofensine operates through pathways characteristic of the Small Molecule class, interacting with target receptors and downstream signaling cascades to produce its observed effects.
Published Research
The following studies are indexed from PubMed and peer-reviewed journals:
Safety Profile
Research-only. Potent CNS stimulant. Can cause insomnia, elevated heart rate, and dry mouth. Half-life is extremely long, leading to accumulation in the system.
| Side Effect | Incidence | Severity |
|---|---|---|
| Insomnia | ~15% of users | moderate |
| Dry Mouth | ~20% of users | mild |
| Elevated Heart Rate | ~12% of users | moderate |
Sourcing Tesofensine for Research
If you're looking to source Tesofensine for laboratory research, our vendor directory compares pricing, purity testing, and COA verification from independently vetted suppliers.
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Full Research Profile
Tesofensine — dosing, interactions, timelines & more
Comprehensive compound profile with sourcing information, stacking synergies, and outcome timelines.