AOD-9604
Last reviewed May 27, 2026
Also known as: Advanced Obesity Drug 9604
Quick Answer
AOD-9604 is a gh fragment research compound (not FDA-approved for human use) studied for fat loss without gh side effects. AOD-9604 is a synthetic fragment of human growth hormone studied for its ability to burn fat without the blood sugar or growth side effects of full GH. Research dose: 300–300 mcg 7x/wk. Half-life: 1 hours. Available from COA-verified vendors with code PEPTIDEX for up to 20% off.
Where to Source
Ranked by $/mg1Amino Club Best $/mg
$39.99
$49.99Save $10.00
5mg vial
$10.00/mg
99%+ purityCOA · Apr 2026
Use code for 20% off:
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Rankings independent · Research use only
Mimics GH fat-burning domain. Stimulates lipolysis and inhibits lipogenesis by acting on beta-3 adrenergic receptors in fat tissue, without binding to the GH receptor.
Where to Buy AOD-9604
COA-verified vendors · Use code PEPTIDEX for up to 20% off
* Prices for research peptide acquisition. Not therapeutic products.
| Vendor | Purity | List Price | With PEPTIDEX | Code | Shop |
|---|---|---|---|---|---|
Amino ClubEditor's Pick | 99%+ | $49.995 mg | $39.99Save 20% | PEPTIDEX | * Research vendor — verify your regional regulations before purchase. Shop |
| 98%+ | $59.995 mg | $30.00Save 50% | PEPTIDEX | * Research vendor — verify your regional regulations before purchase. Shop |
Amino ClubEditor's Pick
$49.99 · 5 mg$39.99−20%
Use code PEPTIDEX for 20% off at Amino Club.
* Research vendor — verify your regional regulations before purchase.
Shop at Amino Club$59.99 · 5 mg$30.00−50%
Use code PEPTIDEX for 50% off at Ascension Peptides.
* Research vendor — verify your regional regulations before purchase.
Shop at Ascension Peptides§ Mechanism of Action
Mimics GH fat-burning domain. Stimulates lipolysis and inhibits lipogenesis by acting on beta-3 adrenergic receptors in fat tissue, without binding to the GH receptor.
§ Primary Benefits
- 1Fat loss without GH side effects
§ Clinical Evidence
AOD-9604 lipolysis stimulation in preclinical models
Ng et al. demonstrate AOD-9604 stimulates lipolysis and inhibits lipogenesis in adipose tissue without affecting IGF-1 or glucose tolerance.
PreclinicalAOD-9604 clinical safety six randomized controlled trials
Heffernan et al.: Pooled analysis of 6 RCTs showing AOD-9604 is well-tolerated with a safety profile similar to placebo despite limited efficacy signals.
ModerateAOD-9604 Phase IIb trial short-term fat reduction
12-week Phase IIb trial: 1mg/day AOD-9604 produced 2.6 kg weight loss vs 0.8 kg placebo, with reductions in abdominal fat and improved lipid profiles.
ModerateSafety and Efficacy of Approved and Unapproved Peptide Therapies for Musculoskeletal Injuries and Athletic Performance.
A 2026 review found that many unapproved peptides demonstrate favorable tissue repair and metabolic outcomes in animal models, though rigorous human safety data remain scarce. The study investigated the pharmacological mechanisms and regulatory status of various sports medicine peptides.
EmergingTherapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.
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EmergingA novel inhibitor of pyruvate dehydrogenase kinase stimulates myocardial carbohydrate oxidation in diet-induced obesity.
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PreclinicalSimplifying and expanding the screening for peptides <2 kDa by direct urine injection, liquid chromatography, and ion mobility mass spectrometry.
A 2016 study demonstrated a highly sensitive screening method for detecting prohibited peptides under 2 kDa, such as GHRPs and TB-500, directly from urine. The liquid chromatography and mass spectrometry assay successfully identified peptide administration in human elimination samples, improving anti-doping control measures.
ModerateEffect of Intra-articular Injection of AOD9604 with or without Hyaluronic Acid in Rabbit Osteoarthritis Model.
In a 2015 study, researchers found that intra-articular injections of AOD9604 enhanced cartilage regeneration in a rabbit model of osteoarthritis. Furthermore, the study demonstrated that combining AOD9604 with hyaluronic acid was more effective at reducing cartilage degeneration than either treatment alone.
PreclinicalHuman sports drug testing by mass spectrometry.
A 2017 review demonstrated that mass spectrometry has become an indispensable tool in modern sports drug testing. The paper detailed its critical role in detecting diverse substances, including peptidic drugs, anabolic agents, and nucleotide-derived therapeutics.
EmergingDetecting peptidic drugs, drug candidates and analogs in sports doping: current status and future directions.
A 2014 review found that advanced mass spectrometric and immunological methods can successfully detect the misuse of various peptidic drugs, including TB-500 and CJC-1295, in sports doping. However, researchers noted a gap remains between technical capabilities and routine analytical practice.
Emerging§ Safety Profile
Research-only. Received GRAS status from FDA as food supplement ingredient. Banned by WADA. Phase 3 trial discontinued due to insufficient efficacy.
See our evidence grading methodology for how we evaluate and grade peptide safety data.
§ Dosing Protocol
* Dosing data from published literature — not a human use recommendation.
RouteSubQ
Dose Range300–300 mcg
Frequency7x/wk
TimingMorning fasted
Cycle Length12–12 weeks
BAC Water2.5 ml / 5mg vial
Take on empty stomach. No effect on blood sugar or IGF-1.
§ Pharmacokinetics
⏱️ Half-Life: 1h
Plasma concentration over time§ Regulatory
🇺🇸USA
Research Only🇨🇦Canada
Research Only🇬🇧UK
Unregulated🇪🇺EU
Unregulated🇦🇺Australia
FDA/TGA ApprovedLast updated: 2026-01 · Laws change frequently. Verify current status in your jurisdiction.
§ Expected Outcomes
Weeks 2–4
Early lipolysis effects, especially in abdominal area
Month 2–3
Noticeable fat reduction in visceral stores; improved metabolic markers
Long-term
Sustained fat loss; may preserve muscle mass better than caloric restriction alone
§ Adverse Effects
| Side Effect | Incidence | Severity |
|---|---|---|
Injection site reaction | ~5% of users | mild |
Mild nausea | ~3% of users | mild |
Where to Source AOD-9604 for Research
Finding verified, high-purity AOD-9604 requires rigorous COA verification. We independently evaluate vendors based on third-party HPLC testing, purity thresholds (≥98%), and batch-specific documentation.
View COA-Verified AOD-9604✓ Third-party tested·✓ US shipping·✓ COA on every batch
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§ Comparisons
§ Community Stacks
Fat Loss Focus Stack
Maximum fat loss through targeted metabolic optimization and direct adipose tissue mobilization
Cite This Page
⚠️ Educational only · Not medical advice · For research use only. Information on this page is compiled from peer-reviewed literature and is intended strictly for educational and informational purposes. Peptides discussed may be unapproved research chemicals — consult a licensed healthcare professional before considering any peptide compound. Read our full disclaimer
Affiliate disclosure: PeptiDex may earn commissions from purchases made through vendor links on this page. This does not affect our editorial ranking or vendor recommendations — we exclusively feature vendors that pass independent COA verification. See our methodology · Editorial policy
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