What Is Selank?
Selank (TP-7) is classified as a anxiolytic peptide peptide. Modulates GABA/serotonin neurotransmitter systems. Enhances immune function by influencing IL-6 and T-helper cell balance. Stabilizes enkephalin levels.
It is extensively evaluated in laboratory and clinical settings for its potential to drive anxiety reduction, mental clarity, mood. Researchers target Selank for its ability to interact with specific cellular and molecular pathways, making it a compound of significant interest across multiple therapeutic domains.
Very safe profile. No reported dependence or withdrawal. Approved as anxiolytic in Russia. Not FDA-approved in US.
How Does Selank Work?
Modulates GABA/serotonin neurotransmitter systems. Enhances immune function by influencing IL-6 and T-helper cell balance. Stabilizes enkephalin levels.
At the molecular level, Selank operates through pathways characteristic of the Anxiolytic Peptide class. By interacting with target receptors and downstream signaling cascades, the compound initiates biological responses associated with anxiety reduction, mental clarity, mood.
Expected Research Timeline
Weeks 2–4
Stable anxiolytic effects without sedation; improved sleep onset
Months 2–3
Adaptive reduction in baseline anxiety; improved immune markers in some studies
Long-Term
Effects generally require cycling; tolerance is low compared to benzodiazepines
What Does the Research Say?
The following are key findings from peer-reviewed studies on Selank, indexed on PubMed and equivalent databases:
[1]Selank anxiolytic effects in humans
Clinical trial demonstrates Selank's anxiolytic efficacy in patients with generalized anxiety disorder, comparable to benzodiazepines but without sedation or dependence.
Evidence: moderate[2]Selank anti-anxiety effects comparable to benzodiazepines
Study confirms Selank provides significant anti-anxiety effects comparable to benzodiazepine treatment, with added cognitive enhancement and no addictive potential.
Evidence: moderate[3]Selank increases BDNF in hippocampus and prefrontal cortex
Selank increases BDNF production in the rat hippocampus and prefrontal cortex, preventing ethanol-induced memory impairment and enhancing synaptic plasticity.
Evidence: preclinical[4]Selank modulates GABA receptor gene expression
Molecular study showing Selank influences GABA-A receptor subunit gene expression, providing mechanism for its anxiolytic effects without sedation.
Evidence: preclinicalSafety & Side Effects
Very safe profile. No reported dependence or withdrawal. Approved as anxiolytic in Russia. Not FDA-approved in US.
| Side Effect | Incidence | Severity |
|---|---|---|
| Mild fatigue | ~5% of users | mild |
| Nasal irritation | ~6% of users | mild |
| Mood fluctuation | ~3% of users | mild |
FDA Status: Not Approved for Human Therapeutic Use
Selank is not currently FDA-approved for human use. It is available for research purposes only. Always consult a licensed healthcare provider.
How Is Selank Used?
Route
Nasal
Dose Range
300–300 mcg
Frequency
7x/wk
Cycle
8–8 wk
Timing: Morning or as needed
Notes: Nasal spray: 1-2 sprays per nostril. Non-addictive; can be used daily.
All dosing information reflects parameters reported in published research literature and is not intended as clinical guidance. Usage of any peptide should be supervised by a qualified healthcare professional.
Selank vs. Related Compounds
Where to Source Selank for Research
Purchasing ultra-high purity, laboratory-grade peptides is critical for verifiable research. We only recommend vendors providing independent, third-party HPLC Certificates of Analysis (COA).
Disclosure: PeptiDex may earn a commission from purchases. This does not affect our recommendations. We exclusively feature vendors that pass our strict quality verification protocols.
Frequently Asked Questions
What is Selank?
Selank is a anxiolytic peptide peptide. Modulates GABA/serotonin neurotransmitter systems. Enhances immune function by influencing IL-6 and T-helper cell balance. Stabilizes enkephalin levels.
What are the primary research benefits of Selank?
Published research identifies primary mechanisms targeting: Anxiety reduction, mental clarity, mood. These findings come from 4+ peer-reviewed studies indexed in our database.
What is the half-life of Selank?
In published pharmacokinetic data, Selank demonstrates a half-life of approximately 0.5 hours.
Is Selank FDA approved?
Selank is not currently FDA-approved for human therapeutic use. It is classified as a research compound and is studied under investigational protocols. Always consult a healthcare provider.
What are common side effects of Selank?
Reported side effects in published literature include Mild fatigue (~5% of users), Nasal irritation (~6% of users), Mood fluctuation (~3% of users). Most are classified as mild in severity.
How is Selank administered?
In research settings, Selank is typically administered via Nasal. Nasal spray: 1-2 sprays per nostril. Non-addictive; can be used daily.
Sources
- Selank anxiolytic effects in humans. View on PubMed
- Selank anti-anxiety effects comparable to benzodiazepines. View on PubMed
- Selank increases BDNF in hippocampus and prefrontal cortex. View on PubMed
- Selank modulates GABA receptor gene expression. View on PubMed